Evidence check: Menopause Check in the context of Wechseljahre

A Menopause Check (Wechseljahre test) typically includes hormone measurements (FSH, estradiol) and sometimes DNA variants linked to age at menopause (e.g., in MCM8, BRSK1). However, the evidence for these genetic markers is weak: GWAS studies show small effect sizes with limited predictive power for individuals. The test cannot diagnose whether menopause is imminent or predict symptom severity. Hormonal fluctuations are normal, and menopause timing is strongly influenced by age, genetics, and lifestyle. A finding suggesting earlier menopause should not cause undue worry but rather prompt medical follow-up. The evidence for consumer menopause tests is mixed: there is some scientific basis, but practical utility is limited. Safety note: Do not make medical decisions based solely on this test; consult a gynecologist for symptoms or fertility concerns.