Evidence check: CRP Entzündung in the context of Schlaf

C-reactive protein (CRP) is a well-established inflammatory marker produced in the liver. Sleep deprivation and poor sleep quality can elevate CRP through mechanisms such as sympathetic activation and increased pro-inflammatory cytokines. Observational studies show modest associations between short sleep (<6 h) or poor sleep quality and higher CRP, especially in individuals with sleep apnea or obesity. However, effect sizes are small to moderate, and clinical relevance for healthy individuals remains uncertain. MyBody-X offers CRP blood tests, but a single elevated value without clinical context is not diagnostic. Evidence is based on epidemiological data, not interventional trials. Therefore, actionable insights for sleep optimization are limited. Caveat: CRP is non-specific; infections, stress, smoking, and other conditions also raise it. Improving sleep hygiene may lower CRP, but individual responses vary. Evidence grade: human-moderate.