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Evidence check: VKORC1 in the context of Darmgesundheit

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Evidence check: VKORC1 in the context of Darmgesundheit

VKORC1 is a key gene in vitamin K metabolism and warfarin sensitivity. Direct evidence linking it to gut health is lacking. While gut bacteria produce vitamin K, VKORC1 variants primarily affect coagulation, not microbiome composition or intestinal barrier function. MyBody-X may include this gene in nutrigenetic panels, but no robust studies connect it to gut health outcomes. Evidence grade: mechanistic/unclear. Consumers should not infer specific dietary advice for gut health from VKORC1 alone.

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