{"count":2,"index":{"built_at":"2026-07-28T03:03:04.940452+00:00","public_records":55311,"revision":"b5e85e40d117079d2d47438a"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: VKORC1 in the context of Darmgesundheit"},"results":[{"answer":"VKORC1 is a key gene in vitamin K metabolism and warfarin sensitivity. Direct evidence linking it to gut health is lacking. While gut bacteria produce vitamin K, VKORC1 variants primarily affect coagulation, not microbiome composition or intestinal barrier function. MyBody-X may include this gene in nutrigenetic panels, but no robust studies connect it to gut health outcomes. Evidence grade: mechanistic/unclear. Consumers should not infer specific dietary advice for gut health from VKORC1 alone.","area":"gesundheit","canonical_id":"gesundheit:canonical-119b3f1b32d56807e2577a34","id":"public-80703256062a60acd882827e","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: VKORC1 in the context of Darmgesundheit","score":24.75388531,"snippet":"VKORC1 is a key gene in vitamin K metabolism and warfarin sensitivity. Direct evidence linking it to gut health is lacking. While gut bacteria produce vitamin K, VKORC1 variants primarily affect coagulation, not microbiome composition or intestinal barrier function. MyBody-X may include this gene in nutrigenetic panels, but no robust studies connect it to gut health outcomes. Evidence grade: mechanistic/unclear. Consumers should not infer specific dietary advice for gut health from VKORC1 alone.","sources":[],"title":"Evidence check: VKORC1 in the context of Darmgesundheit","url":"https://tikki.wiki/wissen/gesundheit/frage/public-80703256062a60acd882827e/evidence-check-vkorc1-in-the-context-of-darmgesundheit/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The combination of Cardio Risk Check with gut health (Darmgesundheit) is not supported by the provided context. The knowledge fragments contain no studies or mechanisms linking cardiovascular risk markers directly to gut microbiota. Some commercial DNA tests advertise such combos, but evidence is weak or purely hypothetical. Cardiovascular risk factors like cholesterol, blood pressure, or genetic variants (e.g., CYP2D6, VKORC1) are only mentioned in relation to drug metabolism, not gut health. While the gut microbiome can influence cardiovascular risk via inflammation, this is not addressed in the given data. Consumers should be cautious about such combined tests and not rely on unverified claims. Evidence: unclear. Sources: none.","area":"gesundheit","canonical_id":"gesundheit:canonical-0b929ed8762f0241ec1cf032","id":"public-3d0abf100dd3683188536b73","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Cardio Risk Check in the context of Darmgesundheit","score":22.67048379,"snippet":"The combination of Cardio Risk Check with gut health (Darmgesundheit) is not supported by the provided context. The knowledge fragments contain no studies or mechanisms linking cardiovascular risk markers directly to gut microbiota. Some commercial DNA tests advertise such combos, but evidence is weak or purely hypothetical. Cardiovascular risk factors like cholesterol, blood pressure, or genetic variants (e.g., CYP2D6, VKORC1) are only mentioned in relation to drug metabolism, not gut health. While the gut microbiome can influence cardiovascular risk via inflammation, this is not addressed in the given data. Consumers should be cautious about such combined tests and not rely on unverified c","sources":[],"title":"Evidence check: Cardio Risk Check in the context of Darmgesundheit","url":"https://tikki.wiki/wissen/gesundheit/frage/public-3d0abf100dd3683188536b73/evidence-check-cardio-risk-check-in-the-context-of-darmgesundheit/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}