Evidence check: TSH Schilddrüse in the context of menopause

TSH levels can fluctuate during menopause due to estrogen decline affecting the hypothalamic-pituitary-thyroid axis. Elevated TSH may indicate subclinical hypothyroidism, which becomes more common in perimenopause. However, the relationship is complex: stress, weight gain, or iodine deficiency also influence TSH. The provided context lacks direct studies on TSH and menopause, so the evidence is rated as 'mixed' – there are population-level observations but no conclusive causal evidence from the given sources. Individual results require clinical interpretation.