{"count":3,"index":{"built_at":"2026-07-27T02:54:54.671241+00:00","public_records":55311,"revision":"b40d3ea78c607332a3ceca39"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: TSH Schilddrüse in the context of menopause"},"results":[{"answer":"TSH levels can fluctuate during menopause due to estrogen decline affecting the hypothalamic-pituitary-thyroid axis. Elevated TSH may indicate subclinical hypothyroidism, which becomes more common in perimenopause. However, the relationship is complex: stress, weight gain, or iodine deficiency also influence TSH. The provided context lacks direct studies on TSH and menopause, so the evidence is rated as 'mixed' – there are population-level observations but no conclusive causal evidence from the given sources. Individual results require clinical interpretation.","area":"gesundheit","canonical_id":"gesundheit:canonical-9af21cffea3af6c03ab81377","id":"public-13416e98180161e0f8b0e196","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: TSH Schilddrüse in the context of menopause","score":25.88484552,"snippet":"TSH levels can fluctuate during menopause due to estrogen decline affecting the hypothalamic-pituitary-thyroid axis. Elevated TSH may indicate subclinical hypothyroidism, which becomes more common in perimenopause. However, the relationship is complex: stress, weight gain, or iodine deficiency also influence TSH. The provided context lacks direct studies on TSH and menopause, so the evidence is rated as 'mixed' – there are population-level observations but no conclusive causal evidence from the given sources. Individual results require clinical interpretation.","sources":[],"title":"Evidence check: TSH Schilddrüse in the context of menopause","url":"https://tikki.wiki/wissen/gesundheit/frage/public-13416e98180161e0f8b0e196/evidence-check-tsh-schilddruese-in-the-context-of-menopause/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The question about TSH and thyroid in menopause is clinically relevant, but the provided knowledge context contains no specific studies or genes on this topic. TSH levels often rise slightly with age and during perimenopause, but this does not automatically indicate hypothyroidism requiring treatment. Genetic testing for TSH-associated variants (e.g., in PDE8B, TSHR) has very small effect sizes and is not recommended in routine diagnostics. Evidence for direct TSH genetic testing in the context of menopause is weak; clinical guidelines rely on blood markers (TSH, fT4) and symptoms, not genetics. Without concrete sources in the context, evidence must be rated as 'unclear'. Caution: a genetic test does not replace medical evaluation for menopausal symptoms possibly linked to thyroid function.","area":"gesundheit","canonical_id":"gesundheit:canonical-dab9e77e937a43a425a3f33b","id":"public-337d43a9fa77bd3a6b6ac4be","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: TSH Schilddrüse in the context of Wechseljahre","score":25.16101471,"snippet":"The question about TSH and thyroid in menopause is clinically relevant, but the provided knowledge context contains no specific studies or genes on this topic. TSH levels often rise slightly with age and during perimenopause, but this does not automatically indicate hypothyroidism requiring treatment. Genetic testing for TSH-associated variants (e.g., in PDE8B, TSHR) has very small effect sizes and is not recommended in routine diagnostics. Evidence for direct TSH genetic testing in the context of menopause is weak; clinical guidelines rely on blood markers (TSH, fT4) and symptoms, not genetics. Without concrete sources in the context, evidence must be rated as 'unclear'. Caution: a genetic ","sources":[],"title":"Evidence check: TSH Schilddrüse in the context of Wechseljahre","url":"https://tikki.wiki/wissen/gesundheit/frage/public-337d43a9fa77bd3a6b6ac4be/evidence-check-tsh-schilddruese-in-the-context-of-wechseljahre/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"TSH (thyroid-stimulating hormone) measurement is a well-established screening tool for thyroid dysfunction. Hypothyroidism commonly presents with fatigue, lethargy, and weight gain. However, fatigue is a highly nonspecific symptom with many potential causes (iron deficiency, sleep disorders, stress, infections, etc.). A single TSH value, as offered in the MyBody-X Menopause Check, can provide a clue but cannot replace a clinical diagnosis. The evidence for TSH utility in fatigue is strong (standard medical practice), but interpretation requires context. If TSH is abnormal or fatigue persists, a full thyroid panel (fT3, fT4, antibodies) and medical evaluation are needed. Limitations include diurnal variation and medication interference. Overall, TSH is a useful initial biomarker for fatigue, but not definitive on its own.","area":"gesundheit","canonical_id":"gesundheit:canonical-f67bf2bad43a30958689e03a","id":"public-cf32f2487a6dfa794f7b5223","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Is TSH Schilddrüse useful for Müdigkeit?","score":23.06764407,"snippet":"TSH (thyroid-stimulating hormone) measurement is a well-established screening tool for thyroid dysfunction. Hypothyroidism commonly presents with fatigue, lethargy, and weight gain. However, fatigue is a highly nonspecific symptom with many potential causes (iron deficiency, sleep disorders, stress, infections, etc.). A single TSH value, as offered in the MyBody-X Menopause Check, can provide a clue but cannot replace a clinical diagnosis. The evidence for TSH utility in fatigue is strong (standard medical practice), but interpretation requires context. If TSH is abnormal or fatigue persists, a full thyroid panel (fT3, fT4, antibodies) and medical evaluation are needed. Limitations include d","sources":[],"title":"Is TSH Schilddrüse useful for Müdigkeit?","url":"https://tikki.wiki/wissen/gesundheit/frage/public-cf32f2487a6dfa794f7b5223/is-tsh-schilddruese-useful-for-muedigkeit/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}