Is hsCRP useful for longevity?

Yes, hsCRP (high-sensitivity C-reactive protein) is a useful biomarker for longevity, as it indicates chronic low-grade inflammation—a key driver of aging and age-related diseases such as cardiovascular disease, diabetes, and cognitive decline. Numerous large-scale human studies show that elevated hsCRP levels are associated with increased all-cause mortality. However, hsCRP is not a standalone longevity test; it must be interpreted alongside other risk factors (lipids, blood pressure, lifestyle). A single measurement can be skewed by acute infections or injuries, so serial measurements are recommended. The evidence is human-strong, but clinical decisions should be made by a physician. It serves as a valuable screening tool, not a definitive diagnosis.