Whether magnesium is useful for allergies cannot be answered with certainty based on current evidence. Mechanistically, magnesium plays a role in mast cell stabilization and has anti-inflammatory properties, which could theoretically dampen allergic responses. A few small studies suggest possible benefits for seasonal allergic rhinitis, such as reduced nasal symptoms. However, the overall evidence is weak – large, randomized controlled trials are lacking. Magnesium deficiency is relatively uncommon, and supplementation without prior lab testing is not advisable. If a true deficiency is confirmed (e.g., via a red blood cell magnesium test), targeted supplementation may be considered. Safety note: high doses of magnesium, especially magnesium oxide, can cause diarrhea; caution is needed in kidney disease. For allergy sufferers, the cornerstone remains allergen avoidance and guideline-based treatment (antihistamines, possibly immunotherapy). Magnesium is not a substitute but at best an adjunct – and only when deficiency is proven.
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