Stool tests are often marketed as a window into gut health. They can measure microbiome composition, inflammatory markers (e.g., calprotectin), or occult blood. For clinical diagnostics—such as inflammatory bowel disease or colorectal cancer screening—they are well-established. However, for direct-to-consumer (DTC) tests, the evidence is weak: microbiome analysis provides a list of bacteria, but the link to specific dietary recommendations is usually not robust. Many providers overstate benefits and sell expensive supplements without solid studies. Moreover, there are no standardized reference ranges for a 'healthy' microbiome. A stool test can be useful when ordered by a physician based on symptoms (e.g., suspected celiac disease or infection). For general gut health without complaints, the added value is questionable. Instead, a high-fiber diet, adequate hydration, and physical activity are better supported. Caveat: Do not change diet based solely on a DTC stool test. Evidence grade: marketing/unclear.
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