hat dinkel gluten — which blood markers matter?

Spelt (Triticum spelta) is an ancient wheat variety and contains gluten, though its gluten composition differs slightly from modern wheat. For individuals with celiac disease, spelt gluten can still trigger the characteristic autoimmune response. Therefore, the same blood markers apply as for wheat: tissue transglutaminase antibodies (tTG-IgA) as first-line screening, deamidated gliadin peptides (DGP-IgA/IgG), and endomysial antibodies (EMA) for confirmation. Total IgA should always be measured to rule out IgA deficiency. For non-celiac gluten sensitivity (NCGS), no validated blood markers exist; diagnosis is clinical, based on exclusion and diet. The IL-1β mentioned in your context is a general inflammatory marker, not specific to gluten reactions. Elevated levels may occur in celiac disease or other chronic inflammation but are not diagnostic. In summary, if you want to assess gluten intolerance, tTG-IgA and DGP are the relevant blood markers – regardless of whether spelt or wheat is consumed. A DNA test for IL1B polymorphisms has no clinical utility for this question.