What to watch with AMH and Wechseljahre?

AMH (Anti-Müllerian Hormone) is a marker of ovarian reserve, reflecting the remaining egg supply. During menopause (Wechseljahre), AMH levels decline and eventually become undetectable. A very low or undetectable AMH can indicate that menopause is approaching or has occurred. However, AMH is not a diagnostic test for menopause – diagnosis relies on clinical criteria (12 months without menstruation) and sometimes FSH measurement. AMH levels vary with cycle phase, age, and assay method. Commercial home tests for AMH are often not standardized and may be misleading. Key limitations: a normal AMH does not rule out early menopause, and a low AMH does not guarantee infertility. The predictive value for timing menopause is moderate at best, especially in women over 40. Always have AMH interpreted by a doctor in the context of your full hormonal profile. Evidence: human-moderate – AMH is well-studied but its ability to predict menopause timing is moderate and not suitable for individual clinical decisions without further context.