Can Ferritin Eisenmangel help with Langlebigkeit?

The question of whether ferritin deficiency (iron deficiency) can promote longevity lacks solid human evidence. In model organisms like C. elegans and mice, iron restriction has been shown to reduce oxidative stress and extend lifespan – but this is mechanistic, not translational to humans. In humans, iron deficiency leads to anemia, fatigue, impaired immunity, and cognitive decline, all of which reduce quality of life and may shorten lifespan. Ferritin is a storage protein; low levels indicate a deficiency that requires treatment. No human studies demonstrate a beneficial effect of iron deficiency on longevity. The evidence is therefore mechanistic/speculative. Caveat: Iron deficiency is a clinically relevant condition that must be evaluated by a physician. Intentionally inducing deficiency is dangerous and not recommended.