What do studies say about APOE Männer?

The rs16969968 variant in the CHRNA5 gene has been linked in GWAS to a slightly higher risk of nicotine dependence. It does not mean you will definitely become addicted, but it may make quitting harder. The effect size is small – many other genetic and lifestyle factors are more important. A single DNA test cannot reliably predict your smoking behavior. If you smoke, this information can serve as an additional clue, but not as a sole basis for decisions.