How are LDL and allergy related?

LDL cholesterol is primarily known for cardiovascular risk, but it also has immunomodulatory properties. Oxidized LDL can promote inflammation, while native LDL may bind allergens and modulate immune responses. Some epidemiological studies suggest an inverse association between LDL levels and allergy risk, but evidence is inconsistent and largely observational. Causal mechanisms remain unclear. Caution: LDL-lowering therapies like statins might theoretically affect allergic responses, but clinical relevance is unproven. No actionable recommendation from these data.