Evidence check: TSH Schilddrüse in the context of sleep

TSH (thyroid-stimulating hormone) is secreted by the pituitary gland and regulates thyroid function. It follows a circadian rhythm with a nocturnal peak. Sleep deprivation or disruption can alter this rhythm, leading to changes in TSH levels. Studies indicate that sleep loss can blunt the nocturnal TSH surge, while thyroid hormones T3 and T4 are less affected. However, effects are individually variable and not sufficient to infer sleep quality from TSH alone. In a MyBody-X test measuring TSH, the time of blood draw is critical. Elevated TSH may indicate hypothyroidism but can also be influenced by poor sleep. Evidence is based on human studies with moderate strength. Clinically, TSH is used for thyroid diagnosis, not sleep assessment. Caveat: Single measurements without sleep context can be misleading.