How are Ferritin Eisenmangel and Schlaf related?

The relationship between ferritin (iron storage), iron deficiency, and sleep is well established. Ferritin is the main iron storage protein. Low ferritin (iron deficiency) can impair sleep through several mechanisms: First, iron is a crucial cofactor for dopamine synthesis and neurotransmitter metabolism. Deficiency can trigger or worsen Restless Legs Syndrome (RLS), characterized by uncomfortable leg sensations and an urge to move during rest, leading to significant sleep onset and maintenance difficulties. Second, iron deficiency may alter sleep architecture, reducing REM sleep duration and overall sleep efficiency. Third, iron deficiency anemia is often linked to fatigue and daytime sleepiness, which paradoxically can further disrupt nighttime sleep. Evidence comes from clinical studies and meta-analyses, especially regarding RLS and iron. However, the evidence for non-anemic iron deficiency without RLS is less robust. Ferritin levels below 30–50 µg/L are considered a risk factor for sleep-related symptoms. A MyBody-X test measures ferritin in blood but cannot provide a medical diagnosis. If you have sleep issues and suspect iron deficiency, consult a physician for clinical evaluation and possible supplementation.