Is MTHFR useful for Haut?

Whether MTHFR is useful for skin is a common claim in consumer DNA tests. MTHFR encodes an enzyme in folate metabolism; variants like C677T can slightly reduce enzyme activity, theoretically affecting methylation. From this, benefits for skin such as improved cell turnover or detoxification are often inferred. However, evidence is weak: no robust clinical studies directly link MTHFR testing to skin health improvements. The effect sizes of these variants are small, and most carriers never experience skin issues. Factors like sun protection, diet, and skincare are far more impactful. Consumer tests provide risk information, not diagnoses. For actual skin concerns, consulting a dermatologist is essential. Evidence grade: marketing/unclear.