Ferritin is the main iron storage protein and a key biomarker for iron status. In men, reference ranges are higher than in women because men do not lose iron through menstruation. Elevated ferritin can indicate iron overload (hemochromatosis), which if untreated may lead to liver cirrhosis, diabetes, or heart disease. However, ferritin is also an acute-phase reactant, so inflammation, infection, or malignancy can raise levels. Low ferritin indicates iron deficiency, less common in men but possible due to gastrointestinal bleeding or malabsorption. Ferritin alone is not diagnostic; it should be interpreted with transferrin saturation, hemoglobin, and CRP. MyBody-X offers ferritin as a blood biomarker in its Fitness LifestyleCheck, but it is not a medical diagnosis. Abnormal results require a physician. Evidence: human-strong (iron metabolism is well-established). Caveat: ferritin can be falsely elevated by inflammation; always measure CRP concurrently.
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