Glucose is the body's primary energy source. For weight loss, the key factor is not glucose itself but the insulin response triggered by carbohydrate intake. Insulin promotes fat storage and inhibits fat oxidation. Sustainable weight loss requires a calorie deficit, regardless of whether calories come from glucose, fat, or protein. However, large blood glucose fluctuations can trigger cravings, making it harder to maintain a deficit. A diet rich in complex carbohydrates, fiber, and protein helps stabilize blood glucose and supports weight management. The evidence is strong: numerous clinical trials link glycemic load, insulin response, and body weight. Caveat: No single nutrient determines weight loss; overall diet quality and energy balance are decisive. Individuals with diabetes or insulin resistance should manage glucose under medical supervision.
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