MyBody-X angle on Ferritin Alltag

The COMT rs4680 (Val158Met) variant affects the breakdown of catecholamines like dopamine and adrenaline. Carriers of the Met allele have lower enzyme activity, potentially leading to higher stress hormone levels. In theory, chronic stress could accelerate skin aging via oxidative damage and inflammation. However, no robust human studies directly link this specific SNP to skin glycation or collagen loss. The evidence is mechanistic and speculative. As a biohacker, you should not rely solely on this SNP. Proven anti-aging strategies—sun protection, adequate sleep, antioxidants (vitamin C, E, polyphenols), and an anti-inflammatory diet—have much stronger evidence. Genetic testing can offer clues but does not replace clinical assessment or lifestyle optimization. Be cautious of exaggerated marketing claims.