The relationship between progesterone and exercise is complex and not fully understood. Progesterone is a sex hormone primarily involved in the female menstrual cycle. Physical activity can influence hormone levels: intense endurance training may lower progesterone in women, potentially leading to cycle disturbances (athletic amenorrhea). Conversely, progesterone may affect respiration and thermoregulation, possibly altering athletic performance during the luteal phase. However, the evidence is mostly mechanistic and based on small studies. The provided context contains no specific data on progesterone and sport. Therefore, caution is warranted: single hormone measurements or genetic tests (e.g., for IL1B or VDR) do not allow direct conclusions about the progesterone–exercise interaction. Individual recommendations should be based on blood values and clinical symptoms.
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