Chronically elevated cortisol, the primary stress hormone, can negatively impact fertility in both women (disrupted menstrual cycles, anovulation) and men (reduced sperm quality and motility). Therefore, managing cortisol is a reasonable target when trying to conceive. Evidence-based approaches include prioritizing sleep (7–9 hours), moderate physical activity (avoiding overtraining), stress reduction techniques like mindfulness or yoga, and a balanced diet low in refined sugar and excessive caffeine. While adaptogens such as ashwagandha or rhodiola are marketed for cortisol lowering, the clinical evidence is mixed and not strong enough for universal recommendation. Safety note: If you are trying to conceive or undergoing fertility treatment, consult a healthcare provider before taking any supplements, as some may interact with hormones or medications. Also, consider broader factors: thyroid function, vitamin D status (VDR gene variant rs2228570 may influence vitamin D metabolism), and overall hormonal balance. A narrow focus on cortisol alone is insufficient; a comprehensive medical workup is essential.
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