Can VKORC1 help with fertility?

VKORC1 is primarily known for its role in vitamin K recycling and warfarin sensitivity. There is no robust scientific evidence that VKORC1 variants directly affect fertility. A few studies explore possible links via vitamin K-dependent proteins in reproductive tissues, but these are mechanistic or speculative. The evidence is weak and not clinically actionable. Consumer DNA tests that claim VKORC1 can help with fertility are overstating the science. If you have a coagulation disorder, VKORC1 testing may guide medication, but it does not address fertility. Safety note: VKORC1 testing is only medically established for warfarin dosing.