How are BDNF and Haut related?

BDNF (Brain-Derived Neurotrophic Factor) is best known for its critical role in the nervous system, supporting neuronal survival, growth, and plasticity. Its connection to skin („Haut“) is less established and remains an area of emerging research. Preclinical studies suggest that BDNF is expressed in skin cells such as keratinocytes and melanocytes, and may influence wound healing, inflammation, and pigmentation. Some observational data link BDNF polymorphisms to inflammatory skin conditions like psoriasis or atopic dermatitis, but findings are inconsistent and largely derived from cell or animal models. Human clinical evidence is scarce, making the overall evidence level mechanistic or unclear. Consumer DNA tests that claim a direct BDNF–skin link overstate the current science. For skin concerns, standard dermatological evaluation and evidence-based treatments are far more reliable than genetic predictions.