What role does FUT2 play in longevity?

The provided context contains no direct evidence regarding the role of FUT2 in longevity. FUT2 (fucosyltransferase 2) determines secretor status and influences gut microbiome composition by modulating epithelial glycosylation. Some studies suggest a link between the microbiome and aging processes, but evidence for a direct connection between FUT2 variants and human longevity is weak and primarily mechanistic. GWAS associations for FUT2 mainly involve vitamin B12 levels and gut microbiota, not lifespan. The MyBody-X contexts mention neither FUT2 nor longevity in this regard. Therefore, an evidence-based statement is not possible. Claiming that FUT2 affects longevity would be speculative and should not be presented as established knowledge. Consumers should understand that single gene variants are rarely direct predictors of complex traits like longevity.