Is SHBG useful for Haut?

SHBG (sex hormone-binding globulin) modulates the bioavailability of testosterone and estradiol. Low SHBG can indicate androgen excess, which is linked to skin issues like acne, seborrhea, or hirsutism, especially in PCOS. However, SHBG is not a validated skin biomarker; its utility for skin health in direct-to-consumer tests lacks clinical evidence. The connection is mechanistic, not based on robust skin-specific studies. A single SHBG value does not diagnose skin conditions. It should be interpreted alongside other hormones (e.g., free testosterone, DHEAS) and clinical evaluation. MyBody-X offers hormone panels, but claims about skin benefits are speculative. Caution: normal SHBG does not rule out skin problems, and low SHBG is not proof of skin disease. Evidence grade: mechanistic/unclear.