MyBody-X angle on FTO Frauen

MyBody-X angle on FTO in women: The FTO gene is strongly associated with BMI in GWAS, especially rs9939609. However, the effect per risk allele is modest (~0.4 kg/m²) and lifestyle factors dominate. In women, hormonal changes (e.g., menopause) further modulate weight. Many DTC tests overstate the clinical relevance of single FTO variants. MyBody-X rates the evidence as GWAS-based, not causal or individually predictive. The test provides insight, not diagnosis. A holistic view including diet, exercise, and metabolic health is essential. Caveat: genetics is not destiny; FTO variants explain only a small fraction of BMI variance.