What role does Ferritin Eisenmangel play in fertility?

Ferritin is a key marker of iron stores, and iron deficiency can negatively impact fertility. Low ferritin may contribute to anovulation, impaired follicular development, and reduced oocyte quality, as iron is essential for DNA synthesis and cellular energy metabolism. Iron deficiency can also affect endometrial receptivity, potentially hindering implantation. The evidence is largely observational; robust RCTs specifically examining iron supplementation for fertility improvement are limited. A ferritin level below 30 ng/mL is generally considered iron deficiency, but the optimal range for fertility is not well established. In couples with unexplained infertility, screening for iron deficiency is reasonable, and correction may be beneficial, but it is not a guaranteed solution. Caution: iron overload (hemochromatosis) can also impair fertility, so supplementation should only be given after confirmed deficiency.