Is Progesteron useful for longevity?

Progesterone is a sex hormone primarily involved in female reproduction. Some animal studies suggest potential neuroprotective and anti-inflammatory effects that could theoretically support longevity. However, robust human evidence is lacking; no clinical trials demonstrate that progesterone supplementation extends lifespan or healthspan in healthy individuals. The evidence level is therefore mechanistic or unclear. In men, unmonitored use may disrupt hormonal balance and cause adverse effects. Without a medical indication and regular lab monitoring, progesterone should not be used for anti-aging purposes. Consumer hormone tests (e.g., finger-stick) are unreliable for guiding such therapy.