How are Homocystein and Fruchtbarkeit related?

Homocysteine, a sulfur-containing amino acid, is linked to fertility when elevated (hyperhomocysteinemia). Research suggests high homocysteine may impair oocyte quality, increase risk of recurrent pregnancy loss, and disrupt endometrial function. In men, it is associated with reduced sperm quality and DNA fragmentation. The proposed mechanisms include oxidative stress, endothelial dysfunction, and impaired methylation. However, the evidence is moderate: most studies are observational, and causality is not firmly established. Supplementation with folate, vitamin B12, and B6 can lower homocysteine and may improve fertility outcomes in some cases. Homocysteine testing is not a routine part of fertility workups but may be considered in unexplained infertility or specific risk factors. MyBody-X tests provide only indicative insights, not medical diagnoses. Clinical evaluation by a specialist remains essential.