What to watch with WeightLoss | SLIM DNA-Test and menopause?
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TIKKI knowledge answer
Combining a DNA-based weight loss test (like the SLIM DNA-Test) with menopause requires realistic expectations. Menopause naturally lowers estrogen, slowing metabolism and shifting fat distribution toward visceral fat. DNA tests can identify genetic variants affecting basal metabolic rate or nutrient processing, but evidence for personalized weight loss diets is weak. Randomized controlled trials show no clear benefit of nutrigenetic diets over standard advice (PMID 37813841). Results are often not reproducible. Crucially, such tests do not replace hormone testing – checking estradiol, TSH, and other markers is more relevant during menopause. Lifestyle factors like resistance training, adequate protein, and sleep have stronger evidence. The test may serve as a motivational tool but should not be the sole basis for dietary changes during menopause.
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