Myths vs facts: Ferritin Eisenmangel and Schlaf

Ferritin is a protein that stores iron and serves as a key marker of iron status. Low ferritin levels indicate iron deficiency, which has been linked to sleep disturbances, particularly Restless Legs Syndrome (RLS). Research suggests that iron deficiency affects dopamine signaling in the brain, contributing to restless legs and poor sleep quality. However, not all sleep issues stem from iron deficiency; factors like stress, caffeine, or other nutrient deficiencies also play a role. A common myth is that higher ferritin always benefits sleep, but excess iron (hemochromatosis) can be harmful. The evidence is moderate: strong associations exist between iron deficiency and RLS, but causal evidence for general sleep problems is limited. A ferritin blood test can be useful but must be interpreted by a doctor. Self-supplementation without diagnosis is risky, especially for men and postmenopausal women, where elevated ferritin may indicate inflammation or iron overload.