Is Vitamin D 25-OH useful for Wechseljahre?

Measuring 25-hydroxyvitamin D (25-OH) during menopause can be useful because declining estrogen increases osteoporosis risk. Vitamin D is critical for calcium absorption and bone health. Evidence links deficiency to higher fracture risk. However, evidence for non-skeletal benefits (e.g., mood, sleep) is weaker and mostly observational. Routine screening without specific risk factors is not universally recommended by guidelines. If deficiency is confirmed, supplementation is beneficial, but high doses without need can cause harm (hypercalcemia). Overall evidence is moderate: clear benefits for bone health, but insufficient support for universal prevention of all menopausal symptoms. Individual factors like sun exposure, diet, and bone density should guide decisions.