What to watch with Fertility Check | Fruchtbarkeits-Test and menopause?

Combining a fertility check with menopause requires caution. Direct-to-consumer (DTC) tests often measure single hormones (e.g., AMH, FSH) or genetic markers (e.g., MTHFR, rs16991615) that fluctuate widely during perimenopause. A single snapshot cannot reliably predict remaining fertility or menopausal stage. Key watchpoints: 1) Hormonal cycles become irregular in perimenopause – one test may mislead. 2) Genetic variants for age at menopause have small effect sizes and are not clinically actionable. 3) Fertility testing during menopause is largely irrelevant because ovarian reserve is naturally depleted. If you have a pregnancy wish during perimenopause, seek medical evaluation (serial hormone panels, ultrasound, antral follicle count). DTC tests can serve as a curiosity but not as a diagnostic tool. Evidence: mostly marketing; no robust clinical trials support combined fertility-menopause DTC panels.