Evidence check: Mikrobiom Test in the context of fertility

The idea that the microbiome – especially the gut and vaginal microbiome – can influence fertility is increasingly being researched. There is evidence that dysbiosis may be linked to inflammation, hormonal imbalances, and reduced conception readiness. However, the evidence for direct causal effects is still limited. Commercial microbiome tests, such as those offered by MyBody-X, can provide a rough overview of bacterial composition, but they are not clinically validated to diagnose or treat fertility issues. Results are heavily influenced by diet, lifestyle, and probiotic use. Moreover, standardized reference values for a 'fertile' microbiome are lacking. Such tests can serve as supplementary information but should not be the sole basis for medical decisions. For unresolved infertility, medical evaluation (hormone status, cycle monitoring, semen analysis) is essential. Evidence: mixed – there are mechanistic and observational studies, but no robust clinical recommendations for using microbiome tests in fertility diagnostics.