Magnesium plays a role in skin aging primarily through its involvement in DNA repair, collagen synthesis, and antioxidant defense. It acts as a cofactor for numerous enzymes that mitigate oxidative stress and support skin barrier function. Some observational studies suggest a link between low magnesium levels and accelerated skin aging, but robust randomized controlled trials demonstrating a causal anti-aging effect on skin are lacking. The evidence is largely mechanistic and preclinical. Adequate magnesium intake from diet (e.g., nuts, seeds, whole grains) is beneficial for overall health, but specific anti-aging claims for skin are not well-supported. Supplementation should only be considered if deficiency is confirmed. Caution: high doses can cause diarrhea and interact with certain medications.
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