Can tTG IgA help with Sport?

The question whether tTG IgA (tissue transglutaminase antibodies) can help with sport is misleading. tTG IgA is a specific biomarker for celiac disease, an autoimmune condition triggered by gluten. Elevated levels indicate untreated celiac disease, which can cause nutrient malabsorption (iron, vitamin D, B12) and impair athletic performance. In that indirect sense, testing might help identify an underlying cause of fatigue or poor recovery. However, there is no evidence that tTG IgA improves sport performance in healthy individuals without celiac disease. The evidence is weak and based on clinical diagnostics, not sports optimization. Screening for celiac disease may be reasonable in athletes with unexplained symptoms, but not as a general sport test. Caution: a negative test does not fully rule out celiac disease, and a positive test requires medical follow-up. In summary, tTG IgA is not a sport biomarker but a medical diagnostic tool.