What role does Triglyceride play in Langlebigkeit?

Triglycerides are a key biomarker of lipid metabolism and are linked to cardiovascular disease, which can impact longevity. Elevated fasting triglycerides (>150 mg/dL) are considered a risk factor for atherosclerosis and cardiovascular events. However, the direct causal role of triglycerides in longevity is complex: they interact with other lipids (HDL, LDL), insulin resistance, and inflammation. Genetic variants (e.g., in APOA5, LPL) can influence triglyceride levels, but the effect on overall lifespan is mostly indirect and modifiable by lifestyle. Evidence is based on epidemiological studies and Mendelian randomization, not on randomized controlled trials for longevity. Caveat: Single biomarker values without context (diet, exercise, medications) are of limited use for lifestyle optimization.