What role does DNA Stoffwechseltest play in Sport?

DNA metabolism tests (e.g., MTHFR, COMT, GSTM1) are often marketed for personalized sports nutrition or supplementation. However, the scientific evidence is weak: while some variants are associated with nutrient or toxin metabolism, robust RCTs showing clear performance benefits from genotype-based adjustments are lacking. Effects are generally small and overshadowed by training, diet, and lifestyle. Moreover, many such tests lack clinical validation. A DNA metabolism test may provide complementary insights but should not be the sole basis for supplement or dietary decisions in sports. Beware of exaggerated marketing claims.