What to watch with Omega-3 Index and Langlebigkeit?

The Omega-3 Index measures the percentage of EPA and DHA in red blood cell membranes and is a well-established marker for cardiovascular health. An index ≥8 % is associated with lower risk of myocardial infarction and sudden cardiac death, supported by numerous observational studies. Its direct link to longevity is less robust: while some cohort studies suggest an inverse association between Omega-3 levels and all-cause mortality, randomized controlled trials are lacking. Additionally, genetic variants (e.g., in the FADS gene cluster) influence endogenous Omega-3 synthesis, meaning the index is not solely diet-dependent. Interpretation should consider that the Omega-3 Index is a risk marker, not a diagnostic test for longevity. It provides useful hints but must be evaluated alongside other biomarkers (e.g., hsCRP, lipid profile) and clinical context. The evidence for a causal extension of lifespan is currently moderate. Consumers should not rely on this single value but adopt a holistic approach to health and aging.