Evidence check: AMH in the context of Langlebigkeit

AMH (anti-Müllerian hormone) is primarily a marker of ovarian reserve used in fertility medicine. Its link to longevity is indirect: higher AMH in midlife is associated with later menopause, and later menopause is associated with lower all-cause mortality and reduced cardiovascular risk. However, this chain relies on observational studies, not RCTs. AMH naturally declines with age, so a single measurement without trajectory has limited predictive value for individual lifespan. Evidence is human-moderate: plausible mechanisms (estrogen exposure, oxidative stress) exist, but no causal proof. MyBody-X offers AMH in its blood test, but the test is not validated for longevity counseling. Caveat: AMH does not reflect biological aging of other organ systems. Using AMH alone for longevity assessment is not recommended.