Myths vs facts: CRP Entzündung and skin aging

CRP (C-reactive protein) is a well-established but non-specific marker of inflammation. A common myth is that CRP directly causes skin aging. In fact, chronically elevated CRP (0.3–1.0 mg/L) is associated with 'inflammaging' – a systemic low-grade inflammation that promotes collagen breakdown, elastin loss, and wrinkle formation. Observational studies link higher CRP to visible skin aging, but the evidence is moderate. CRP itself is not a direct driver; it is a surrogate marker for inflammatory processes influenced by lifestyle (diet, smoking, UV exposure). Lowering CRP alone without addressing root causes is not proven as an anti-aging strategy. Clinically, anti-inflammatory measures such as a Mediterranean diet, adequate sleep, and sun protection are more relevant. Bottom line: CRP testing can provide insight into inflammatory status but is not a direct skin-aging test.