Myths vs facts: Ferritin Eisenmangel and Haut

Ferritin is a storage protein for iron and a key biomarker for the body's iron supply. A common myth is that low ferritin automatically means iron deficiency. In reality, ferritin is also an acute-phase reactant; it can be elevated during inflammation, infection, or chronic disease, potentially masking a concurrent iron deficiency. Another myth is that iron deficiency only causes anemia. In fact, skin changes such as pallor, dry and scaly skin, brittle nails (koilonychia), and hair loss are frequent but often overlooked symptoms. The facts: ferritin levels below 30 µg/l indicate iron deficiency, while levels between 30 and 100 µg/l may reflect functional iron deficiency, especially in the presence of inflammatory conditions. Skin health heavily depends on adequate iron supply because iron is essential for cell division, collagen synthesis, and immune function. Iron deficiency can therefore impair wound healing and increase skin infection susceptibility. Importantly, ferritin measurement should always be interpreted alongside inflammatory markers (e.g., CRP) to avoid misdiagnosis. If iron deficiency with skin symptoms is suspected, a medical workup including a complete iron panel (ferritin, transferrin saturation, soluble transferrin receptor) is recommended.