Is BDNF useful for Sport?

BDNF (Brain-Derived Neurotrophic Factor) is a protein that supports neuroplasticity, learning, and mood. Physical activity, especially aerobic exercise, can increase BDNF levels in blood, which is associated with improved cognitive function and possibly better motor recovery. However, the direct utility of BDNF as a biomarker for sport optimization or training personalization is not yet supported by robust clinical evidence. Consumer DNA tests (e.g., for BDNF variant rs6265) may hint at individual differences in BDNF response to exercise, but effect sizes are small and practical relevance is limited. Blood-based BDNF measurements also suffer from high methodological variability (e.g., time of day, diet, training status). In summary: BDNF is an interesting but not yet mature parameter for sport guidance. Evidence: unclear (no validated data in the provided context). Caveat: No specific studies from the given material.