What role does AMH play in stress?

AMH (Anti-Müllerian Hormone) is primarily a marker of ovarian reserve used in fertility assessment. Its role in stress is not well-established. Some research suggests chronic psychosocial stress may influence AMH levels via the HPA axis, possibly through cortisol-mediated effects on folliculogenesis. However, findings are inconsistent: some studies report negative correlations between stress and AMH, while others find no significant association. AMH is not a validated stress biomarker; established markers include cortisol, alpha-amylase, and inflammatory cytokines. Commercial DNA or blood tests claiming to assess stress via AMH often overstate the evidence. Measurement is also confounded by menstrual cycle phase and hormonal contraception. In summary, AMH should not be used to evaluate stress. For stress-related concerns, clinical evaluation and evidence-based tools are recommended.