Myths vs facts: ApoB and Haut

ApoB (apolipoprotein B) is a core structural protein of LDL and other atherogenic lipoproteins, and a well-established cardiovascular risk marker. Regarding skin health, the evidence is limited and indirect. Some research suggests ApoB may play a role in wound healing and inflammation, particularly in psoriasis, where elevated ApoB levels have been observed. However, it remains unclear whether ApoB is causal or merely a bystander of systemic inflammation. A common myth is that ApoB directly causes acne or skin aging. There is no robust scientific support for this claim. Skin health is primarily influenced by diet, microbiome, UV exposure, and genetics. ApoB testing is relevant for cardiovascular risk assessment, not for dermatological diagnosis. Those seeking to improve skin health should focus on a balanced diet rich in omega-3 fatty acids, antioxidants, and adequate hydration, rather than targeting ApoB levels. The evidence is mostly mechanistic and observational; randomized controlled trials are lacking.