IgG-based food intolerance tests (e.g., from cerascreen, myBody) are often marketed as allergy tests but are scientifically controversial. IgG antibodies merely indicate immune exposure to foods – often a normal response to frequent consumption. Studies show that IgG tests do not reliably diagnose intolerances or allergies. Major allergy organizations (EAACI, AAAAI) advise against them due to high false-positive rates. Risks include unnecessary dietary restrictions, nutrient deficiencies, anxiety, and financial cost. There is a lack of standardized reference ranges and reproducibility. A positive IgG result alone does not justify an elimination diet. For suspected true food allergy or intolerance (e.g., lactose intolerance, celiac disease), validated methods like skin prick tests, specific IgE, or breath tests are recommended. The evidence for IgG testing is 'mixed': mechanistic plausibility exists, but no robust clinical utility has been demonstrated for everyday use.
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