What to watch with tTG IgA and Darmgesundheit?

tTG IgA (tissue transglutaminase IgA) is the primary screening marker for celiac disease. Elevated levels indicate an immune response to gluten, damaging the small intestinal lining and causing gut health issues like malabsorption, diarrhea, or fatigue. Key caveats: a positive test alone does not confirm celiac disease – duodenal biopsy and total IgA measurement (to rule out IgA deficiency) are required. False positives can occur (e.g., in other autoimmune conditions). If tTG IgA is negative but symptoms persist, further testing (e.g., DGP IgG, HLA typing) may be warranted. For confirmed celiac disease, a strict gluten-free diet restores gut health. Note: consumer tests like MyBody-X provide screening results only; medical follow-up is essential. Evidence: human-strong (guidelines).