Evidence check: CRP Entzündung in the context of Fruchtbarkeit

CRP (C-reactive protein) is a non-specific marker of inflammation that has gained attention in fertility contexts. Elevated CRP levels may indicate chronic low-grade inflammation, which is linked to conditions like endometriosis, PCOS, and obesity – all of which can impair fertility. Observational studies suggest that higher CRP is associated with longer time to pregnancy and lower IVF success rates. However, CRP is not a direct cause; it is a downstream marker. Many lifestyle factors (smoking, diet, stress) also raise CRP. Direct-to-consumer CRP tests can provide a snapshot, but they lack the clinical context needed for interpretation. The evidence is human-observational and moderate in strength; no large RCTs have proven that lowering CRP alone improves fertility outcomes. For a comprehensive fertility assessment, clinical evaluation including hormonal panels and imaging is essential. A single CRP value should not drive decisions. In summary, CRP can be a useful adjunct but is not a standalone fertility predictor. Evidence level: human-moderate.