What should I know about ich nehme immer mehr zu und weiss nicht warum?

Unexplained weight gain has many potential causes: medical (thyroid dysfunction, insulin resistance, medication side effects), lifestyle (caloric surplus, poor sleep, chronic stress), and psychological factors. Consumer DNA tests like MyBody-X analyze common SNPs with small effect sizes from GWAS; no RCT proves that diet advice based on these variants leads to meaningful weight loss. Evidence is weak to moderate. While some genes (e.g., FTO) are associated with obesity risk, their predictive power for an individual is low. A clinical workup (blood panel, TSH, HbA1c, cortisol) is more appropriate than a DNA test. MyBody-X tests are not validated for diagnosing weight gain causes. Be cautious of marketing: 'personalized nutrition' often repackages generic healthy eating advice. The lab process may be ISO-certified, but clinical utility remains unproven.